They compare them to the surface of the blood cells of the person needing a transplant. Everyone has their own set of proteins on the surface of their blood cells. The laboratory staff look for proteins called HLA markers and histocompatibility antigens. They check for 10 HLA markers. The result of this test shows how good the HLA match is between you and the person who needs the cells.
A brother or sister is most likely to be a match. There is a 1 in 4 chance of your cells matching. This is called a matched related donor MRD transplant. Anyone else in the family is unlikely to match. This can be very frustrating for relatives who are keen to help. This is called a haploidentical transplant. It's sometimes possible to get a match from someone outside of the family. This is called a matched unrelated donor. To find a matched unrelated donor, it's usually necessary to search large numbers of people whose tissue type has been tested.
So doctors search national and international registers to try to find a match for your relative. Even if you can't donate to your relative, you might be able to become a donor for someone else. You can do this by contacting one of the UK registers. There are different donor registers in the UK.
These work with each other and with international registers to match donors with people who need stem cells. To apply to join the stem cell register, you need to fill in our online form to request a swab pack to complete and post back. Watch our donation animation below for the full story. You need to be aged 16—30 to join our stem cell register. Research has shown that younger donors increase a patients' chance of surviving.
During the coronavirus pandemic, we're doing extra health checks to ensure the safety of our donors and patients. Both these procedures are carried out thousands of times every year and are very safe. Your donation will be completely anonymous and will take place in the UK. Amazingly , your donated cells could go to help someone anywhere in the world!
Depending on the rules in different countries, our Donor Follow-Up team might be able to help you make contact with your recipient if you wanted to — this would be anonymous for the first two years. It was quite cosy especially with heated blankets to allow my blood to flow better. All in all it was quite therapeutic. They fit it to when I was free and when I could get down there, and my employer said I could take any time off I needed '. Our upper age limit is 30 because our research has shown that the younger a donor is, the better chance of survival a patient has.
Once on the register, you could be asked to donate up until you turn You can join the register if you're taking PrEP. But if you're asked to donate between now and when you turn 61 which is on average a 1 in chance then you might not be able to donate if you'd taken PrEP in the previous few months. This is because PrEP interferes with the testing process that all potential donors go through. But if you're asked to donate which is on average a 1 in chance then you might not be able to donate if you've had the vaccine within the previous 28 days.
This is because the antibodies from the vaccine will interfere with the testing process that all potential donors go through. People from minority ethnic backgrounds are more likely to have rarer tissue types, making it harder to find patients from these backgrounds a matching donor.
Stem cell donations are given in hospitals or at a clinic and you can bring someone with you for support. For the first month following your donation you will be contacted regularly to ensure you do not experience any adverse reactions. If you need to take time off work for the procedure you will be entitled to reimbursement of expenses. These details will be covered in your medical interview when the procedures are explained.
Both forms of stem cell collection may involve some temporary discomfort in your bones and any small risks involved will be fully explained before you donate. All you will know is that you are performing a very valuable and life-saving procedure for a person who is in need. NHSBT uses cookies which are essential for the site to work.
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